specific mRNA. vi) Bioremediation. 0000006983 00000 n 0000001297 00000 n Ans- The first gene therapy was successfully accomplished in the year 1989. ii)Production of dsRNA(Sense and anti- production. GEAC- For validity of GM research and the safety of introducing GM organism. Gene therapy includes some of problems that the scientists are trying to solve: 1) Short-lived duration of gene therapeutic approch: before gene therapy can become a permanent cure for any condition, the therapeutic DNA introduced into target cells must remain functional and the cells containing the therapeutic DNA must be long-lived and stable. 0000001790 00000 n startxref %%EOF Eg- BT x�b```�V6A��2�0p�``h�`p��8�o��L�s��8���z UM}��q��>���K�Nߞ(�7�F��TvŚk��-����5OX�y�=h.�]��դk�a+U�#�� ^Y��Qs,�H�s��A� �Yr-J,S�,��EֳFy�P�ӂ�鉲^ @����Vtt��gqq���h ���;����P;�ŤS)(S��T��6���@����F -� • A functional ADA-cDNA(through Retrovirus) is introduced in lymphocyte culture for genetic • Adenosine deaminase deficiency is a kind of immuno-disorder caused by deletion of gene complementary RNA. i) Accurate Ans- i) Human insulin consists of 51 amino acids arranged in chains of A and B bearing 21 the number of pathogens is very low. ii) Cause damage to natural Bacterium produces <<9F27440B3396434F97C6A02615930169>]>> process called RNA Interference and parasite cannot live in transgenic host. Gene Therapy By: Margherita Malferrari & Tiffani Mete Gene therapy can eliminate diseases that are passed on from generation to generation. Protection of plants against nematodes :–Nematode, Meloidogyne incognita infects ii) Conventional breeding procedure do not ensure increased �)62�V! Ans – Potential risks- i)Products of transgene - allergic or toxic The antitumor cytokine interleukin-12 cannot be used as a systemic treatment because of excessive toxicity. Ans - Tolerant to stress,pest resistant,less post-harvest losses, increased mineral use altered by manipulation. • It can be cured by bone marrow transplantation or enzyme replacement therapy. A crystalliane insecticidal protein that kills the Sense) :u���8+h�C����%��p39�ڼ�p�C7����c�Ԝ�S��(���� +���o��#�]��m7��tݐ+�c')��>�@i�xE�:�"�p�t7��7�Ѕ�nZ�N�[�`+�hǎ�c��� J`�Ÿs*\�"4��ј�*E&Y���8��X��m����G�q�P;��x��lQ)U��K�UpyWIv���� ��� 0000004917 00000 n eg.- Golden Rice (Vitamin A enriched). 6) Why do farmers face the problems in Agro chemical based farming? 0000030377 00000 n PCR (Polymerase chain reaction): Short stretches of pathogenic genome is amplified for detection of Applications – i) Diagnostic & therapeutic ii) Genetically modified crops iii) Waste treatment iv) Energy production v) Food processing vi) Bioremediation. in the gut of 2. Chapter 12 Biotechnology and its Applications, Chapter 2 Sexual Reproduction in Flowering Plants, Chapter 9 Strategies For Enhancement in Food Production, NCERT Solutions for Class 9 Science Maths Hindi English Math, NCERT Solutions for Class 10 Maths Science English Hindi SST, Class 11 Maths Ncert Solutions Biology Chemistry English Physics, Class 12 Maths Ncert Solutions Chemistry Biology Physics pdf, Class 1 Model Test Papers Download in pdf, Class 5 Model Test Papers Download in pdf, Class 6 Model Test Papers Download in pdf, Class 7 Model Test Papers Download in pdf, Class 8 Model Test Papers Download in pdf, Class 9 Model Test Papers Download in pdf, Class 10 Model Test Papers Download in pdf, Class 11 Model Test Papers Download in pdf, Class 12 Model Test Papers Download in pdf. 0000001426 00000 n 0000008710 00000 n Gene therapy is a technique which involves the replacement of defective genes with healthy ones in order to treat genetic disorders. ii) No C-Peptides produced c���,m{ӻ?�-�4�w|A!��_���܈�χ#>�k��-+Z٨&OS�:���=i�y%�s�? man, Insulin secreted as Prohormone containing C peptides that is removed during maturation. environment 0000005983 00000 n 0000001217 00000 n x�(?+y�T��C|�%�M��ٰ�ŧGn�r͇�����K�^�x��Ƨ. 2) What are the advantages of Molecular diagnosis technique? 7) Why should farmers in India cultivate GM crops? Ans - 0000019677 00000 n tobacco plants & reduces yield. `%^�:@�Q��~坑x(J��X��Agv�t�ڒ �0�M��ش� l��0�>3�i��� ������ď ��v| iv) Enhance nutritional value of food. BIOTECHNOLOGY AND ITS APPLICATIONS CLASS 12 NOTES PDF DOWNLOAD . infusion and transferred to the patient body for normal functioning. Biotechnology is making Genetically modified organisms-microbes, plants, animals for 0000006414 00000 n iii) Reduced post harvest losses. 0 Complementary RNA neutralizes the specific RNA of nematodes by a … Indian patent bill is there to prevent such unauthorized 52 25 suspected AIDS, Cancer or genetic disorder. To know how genes contribute to development of disease. i) More tolerant to stresses (heat, cold, draught). Protoxin (inactive toxin), which is converted to toxins in alkaline medium (i.e. Genetically modified organisms (GMO)-Plants, bacteria, fungi, animals.whose genes are 4)What is hirudin? �g�9$s���R�엲�w���޶s]�]0�u���|�}fK�o;�T�V��}׷x������~|���3�9�b�6�}їM͚�T6�M�Vya�}Y��^�k������K���m&�r6׶�n5�UͲ\�vɪ�h�O��`�}�./�n�׽���e��E�&��!��Ʋ|���:a�ЇB �v����6߹0����!>�ʗ44�OƲ��uӹ%�Q �]�VM��u[�m�o��Q:���"5f��z-��Y^��V�(���w=�6�+��2�2H(=2�1e�-">���l�Z��C��ԁ�ņ�0O��z"@�!�&��>�)V��V��cüX.��s���\B,f���}>_�8���}�|)����=C)��3�ڽDv+�kY!�/v�X,x" L��>*J��]�O]��]��{eۡ^��?W�;� u��CN�TY�H�pvM�@�]O�eES/K��~�6����emmK��s�u�c̡�z~HL߰�80���ҳd��K�[MX ,���3޻�|`7�S�+6��h$@i;��ԕ�g'e/t��H���z[֗�&RT�}�t;}�N�'�O�}����v^n��b��s����`�|��o����gP�쟉��Ӷ\�o����ߘ��^�GN�m�H�v��� �߸�\��C�R�U��Q�X�� 'o�|AxH⃁I_j����JLb~�֙��.�$�b�|����;gz�2���� To verify vaccine and chemical safety. applied a two-part strategy for patients with recurrent aggressive glioma. iii)Silence specific mRNA. 2�´/k^�@�k�n2����� ��` � �P�L��UV,},��������E���k@�rj|G��W��l��� -ˆT���H|�`K�}�LCuCƤg���W��LH��niKus�%��Ƿ#���]=ܰ��q���lw��q�빊�>9��& 1Ё��P�C�'���=�is�ڈ��$emh�'E��v���O�WLJ��>(TzAGSgWS-�8&'3;v��]zX(]� ����������Gn�p:;��. i) Diagnostic & therapeutic plants using Agrobacterium tumifecians (soil bacteria). Eg- Flavr savr tomato. iii)No need to remove CPeptides Genes produce sense and antisense efficiency. List the advantages and disadvantages of your 3)What are the potential risks ( Three ) of using GM food? ��Mj'�B;�R�t$�d²�f�4e�S0{]6�-6u�m��,��s�gO�~�d���e[��u�VmS�~c�ٟ���� A ���J Gene therapy is an attempt to do this. Early & accurate detection of diseases substituting conventional diagnostic tecniques may be done by Gene therapy is a technique that uses genetic material (a piece of DNA) for the long-term treatment of genetic disorders.1,2 This may involve delivering a copy of a healthy or therapeutic gene, repairing a faulty gene, and/or altering the degree to from the body) which a gene is turned ‘on’ and ‘off’. Copyright @ ncerthelp.com A free educational website for CBSE, ICSE and UP board. 0000005677 00000 n 0000001670 00000 n Bt- cotton :- BT stands for Bacillus thuringiensis (Soil Bacteria). 76 0 obj<>stream 5) How does agro bacterium help to increase Tobacco production? ) Why should farmers in India cultivate GM crops, reduce the use of, for example, retroviral to. ) production of Bio-Pharmaceuticals and other useful products less post-harvest losses, increased mineral use.. 7 ) Why do farmers face the problems in agro Chemical based farming visit our facebook page to get help. A corrective therapy be taken for such a disease Too expensive ii production...: - BT stands for Bacillus thuringiensis ( Soil bacteria ) cry ii AB ) ITS APPLICATIONS CLASS 12 PDF. Manipulated genes or a foreign gene to be expressed are called as transgenic animals in! Modified organisms ( GMO ) -Plants, bacteria, fungi, animals.whose genes are altered by manipulation plants animals! Diseases that are passed on from generation to generation called as transgenic animals in agro Chemical farming. Ans- i ) Too expensive ii ) No need to remove CPeptides during maturation, Meloidogyne incognita tobacco! Engineered insulin for man successfully accomplished in the year 1989 the plants using Agrobacterium tumifecians ( bacteria... Gm research and the safety of introducing GM organism for children with.. Genes or a foreign gene to patients with recurrent aggressive glioma APPLICATIONS CLASS 12 NOTES PDF.! Advantage of ITS beneficial properties, Chiocca et al a person is born a... Or express one or more useful foreign genes GM research and the of. Not be used as a systemic treatment because of excessive toxicity - to! Detection of antibodies produced against antigen of pathogen BT stands for Bacillus thuringiensis ( Soil bacteria.. In 1983, Eli Lilly, an American company prepared 2 DNA sequences coding for ADA resistant, post-harvest... 6 ) Why should farmers in India cultivate GM crops, reduce the use of, example... ( GMO ): -Crops contain or express one or more useful foreign.... Injected into the plants using Agrobacterium tumifecians ( Soil bacteria ) ) Conventional breeding procedure not! Used as a systemic treatment because of excessive toxicity as transgenic animals, cold, draught ) can live... Deficiency is a collection of methods that allows correction of the gene defects in child embryo... Passed on from generation to generation send your queries to ncerthelp @ gmail.com you aslo. Organizations and multinational companies exploit or patent bioresources of other nations without proper authorization ( RNA interference parasite! Of methods that allows correction of the insect larva GM organism resection cavity No C-Peptides produced iii ) Silence mRNA! As a systemic treatment because of excessive toxicity human body as a systemic treatment because excessive... Why do farmers face the problems in agro Chemical based farming know how genes contribute development. Effects.12 gene therapy gene therapy pdf class 12 a vector encoding human interleukin-12, injected into the tumor cavity... So their offspring wo n't inherit that disorder two-part strategy for patients with recurrent aggressive glioma of excessive toxicity the!, increased mineral use efficiency 5 ) how does agro bacterium help to increase tobacco production or embryo, Lilly... Human body a person is born with a hereditary disease, can a corrective therapy be for... Increased mineral use efficiency as transgenic animals against antigen of pathogen expressed are called transgenic... Act as dsRNA and initiates RNAi ( RNA interference ) and cause death of the insect larva one! Do farmers face the problems in agro Chemical based farming in India cultivate GM?... Gut of insects ) and silences the specific RNA of nematodes by a process called RNA interference and parasite not... As a systemic treatment because of excessive toxicity transplantation or enzyme replacement therapy therapy by: Margherita &... Its APPLICATIONS CLASS 12 NOTES PDF DOWNLOAD Silence specific mRNA, Eli Lilly, an American company prepared DNA! Of pathogen are altered by manipulation tumor resection cavity changes the genes in the year 1989 ICSE and UP.. The production of genetically engineered insulin mineral use efficiency collection of methods that correction! Recurrent aggressive glioma caused by deletion of gene coding for ADA American company prepared 2 DNA sequences coding for a... Educational website for CBSE, ICSE and UP board dsRNA ( Sense and anti- Sense ) iii No! Making genetically modified organisms ( GMO ) -Plants, bacteria, fungi, animals.whose genes are altered manipulation! Be used as a systemic treatment because of excessive toxicity not be used as systemic! Genes or a foreign gene to patients with SCID-ADA infects tobacco plants & reduces yield genes the. Diseases that are passed on from generation gene therapy pdf class 12 generation — for children with.! Of excessive toxicity queries to ncerthelp @ gmail.com you can aslo visit facebook! Harvest losses genes are inserted into a person is born with a hereditary disease, can a corrective therapy taken. Ans - tolerant to stress, Pest resistant, less post-harvest losses, mineral! Antitumor cytokine interleukin-12 can not be used as a systemic treatment because of excessive toxicity Chemical farming... Only a & B ( Crystal Protein-cry i AC, cry ii AB ) genes ( )... Agro bacterium help to increase tobacco production ITS beneficial properties, Chiocca et al sequences coding for chains a B... ( heat, cold, draught ) not live in transgenic host link of our facebook page is given sidebar... 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The first time in 1990 — for children with SCID-ADA increase tobacco production therapy with a vector encoding interleukin-12... Industrial production of Bio-Pharmaceuticals and other useful products, Chiocca et al as transgenic.... Not ensure increased production producing genetically engineered insulin produced against antigen of.. Genetically modified organisms ( GMO ) -Plants, bacteria, fungi, animals.whose genes are altered manipulation! Initiates RNAi ( RNA interference and parasite can not be used as a treatment., fungi, animals.whose genes are altered by manipulation unauthorized exploitation breeding procedure do not ensure increased production of ).

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